Search results for " Type B"

showing 10 items of 31 documents

Consensus recommendation for a diagnostic guideline for acid sphingomyelinase deficiency

2017

Disclaimer: This diagnostic guideline is intended as an educational resource and represents the opinions of the authors, and is not representative of recommendations or policy of the American College of Medical Genetics and Genomics (ACMG). The information should be considered a consensus based on expert opinion, as more comprehensive levels of evidence were not available in the literature in all cases. Background: Acid sphingomyelinase deficiency (ASMD) is a rare, progressive, and often fatal lysosomal storage disease. The underlying metabolic defect is deficiency of the enzyme acid sphingomyelinase that results in progressive accumulation of sphingomyelin in target tissues. ASMD manifests…

0301 basic medicineGuias de prática clínica como assuntomedicine.medical_specialtyConsensusLysosomal storage disorderClinical Decision-MakingMEDLINEDiseaseDiagnosis Differential03 medical and health sciencesSpecial Article0302 clinical medicineInternal medicinemedicineHumansacid sphingomyelin deficiencyGenetic TestingDisease management (health)Intensive care medicineDoenças de Niemann-PickGenetics (clinical)PulmonologistsGenetic testingmedicine.diagnostic_testbusiness.industryNiemann-Pick disease types A and BEvidence-based medicineGuidelineNiemann-Pick Disease Type BNiemann-Pick Disease Type A030104 developmental biologyEndocrinologyPhenotypeSphingomyelin PhosphodiesteraseMutationPractice Guidelines as TopicMedical geneticslysosomal storage disorderbusiness030217 neurology & neurosurgeryAlgorithmsBiomarkersAcid sphingomyelin deficiency
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Burnout syndrome and type A behavior in nurses and teachers in Sicily.

1997

Burnout and Type A behavior were studied in two groups of 50 teachers (26 working in high school and 24 in junior high school) and 50 nurses living and working in Sicily. Each group was composed of 19 men and 31 women. A revised version of the Maslach Burnout Inventory and the Adult and Adolescent Type A Behavior Scale-Revised Form 1 were used to measure burnout and Type A behavior, and a scale of job satisfaction was given. Analysis shows higher scores on stress for nurses, related to the low social acknowledgment of their job. Among nurses, Type A scores were correlated positively with scores on burnout and negatively with ratings of job satisfaction. The teachers showed greater compatib…

AdultCross-Cultural ComparisonMaleSocial ValuesBurnout syndromeeducationNursesBurnoutJob SatisfactionRisk FactorsHumans0501 psychology and cognitive sciencesBurnout ProfessionalGeneral PsychologyCultural CharacteristicsTeaching05 social sciences050301 educationType A and Type B personality theoryType A PersonalityMiddle AgedItalyJob satisfactionFemalePsychology0503 educationSocial psychologypsychological phenomena and processes050104 developmental & child psychologyClinical psychologyPsychological reports
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Type A personality is not associated with poor glycaemic control: Data from cross-sectional and longitudinal surveys of people with type 1 or type 2 …

2017

Diabetes & Metabolism - In Press.Proof corrected by the author Available online since lundi 8 aout 2016

AdultGerontologyAdolescentEndocrinology Diabetes and Metabolism030209 endocrinology & metabolismType 2 diabetesSelf-CareYoung Adult03 medical and health sciences0302 clinical medicineEndocrinologyResearch letterDiabetes mellitusInternal MedicineHumansMedicine030212 general & internal medicinePoor glycaemic controlMortalityAgedAged 80 and overGlycated HemoglobinBehaviorbusiness.industry5-Factor ModelPatternType A PersonalityType A and Type B personality theoryGeneral MedicineMiddle Aged[SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolismMetaanalysis[ SDV.MHEP.EM ] Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolismmedicine.diseaseTraitsEuropeCross-Sectional StudiesDiabetes Mellitus Type 1Diabetes Mellitus Type 2business
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Botulinum toxin A (Botox) and sweating-dose efficacy and comparison to other BoNT preparations.

2004

Abstract Background Botulinum toxin type A (BoNT/A) is 20–50 times more effective than Botulinum toxin type B (BoNT/B) concerning the treatment of muscular hypercontractions [Sloop, R.R., Cole, B.A., Escutin, R.O., 1997. Human response to botulinum toxin injection: type B compared with type A. Neurology 49, 189–194]. Botulinum toxins block motor nerves as well as autonomic fibres [Rand, M.J., Whaler, B.C., 1965. Impairment of sympathetic transmission by botulinum toxin. Nature 206, 588–591]. Objective Purpose of this study was to analyse the dose dependent reduction of sweating using the BoNT/A preparation Botox® and to compare the results with our earlier results analysing Dysport® [Braune…

AdultMalemedicine.medical_specialtyBotulinum ToxinsTime FactorsInjections SubcutaneousSweatingBotulinum toxin aCellular and Molecular NeuroscienceMedicineHumansBotulinum toxin type BAnhidrosisBotulinum Toxins Type AHypohidrosisDose-Response Relationship DrugEndocrine and Autonomic Systemsbusiness.industryStarchBotulinum toxinSurgerySudomotorDose–response relationshipThreshold doseNeuromuscular AgentsAnesthesiaFemaleNeurology (clinical)medicine.symptombusinessBotulinum toxin typemedicine.drugFollow-Up StudiesAutonomic neuroscience : basicclinical
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Type A Behavior Pattern

2012

Aim : To evaluate the presence of type A behavior in patients affected by open-angle glaucoma (OAG) and the possible role of psychophysiological stress as a risk factor for OAG. Materials and methods Fifty patients, 30 women and 20 men, affected by OAG, underwent ophthalmological examination consisting of complete biomicroscopy, tonometry and daily tonometric curve, examination of the visual field by means of computerized perimeter "Octopus 1-2-3," and its assessment with the Glaucoma Staging System 2, morphologic monitoring of the retinal nerve fiber layer with GDx VCC and psychological assessment (Hamilton Anxiety Rating Scale) to evaluate the presence of anxiety and its level; type A/B p…

AdultMalemedicine.medical_specialtyIntraocular pressureOpen angle glaucomaHamilton Anxiety Rating ScaleType A Behavior Patternmedia_common.quotation_subjectGlaucomaManifest Anxiety ScaleTonometry OcularRisk FactorsOphthalmologyHumansMedicinePersonalityPsychological testingIntraocular PressureAgedmedia_commonSettore MED/30 - Malattie Apparato Visivobusiness.industryType A PersonalityType A and Type B personality theoryMiddle Agedmedicine.diseaseOpen-Angle Chronic GlaucomaOphthalmologyquality of lifeChronic DiseaseVisual Field TestsAnxietyFemaleVisual Fieldsmedicine.symptombusinessGlaucoma Open-AngleStress PsychologicalJournal of Glaucoma
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An evaluation of transient elastography in the discrimination of HBeAg-negative disease from inactive hepatitis B carriers

2009

Summary.  Liver biopsy is frequently required in HBeAg-negative disease to determine the stage of fibrosis. It can be difficult to distinguish cohorts with undetectable HBeAg who may have varying degrees of fibrosis due to different stages of disease. We have assessed the utility of transient elastography (TE) to evaluate differences in HBeAg-negative patients. A total of 220 HBsAg-positive individuals were studied: 125 (group 1) had an inactive HBsAg carrier state and 95 (group 2) were HBeAg-negative, anti-HBe-positive patients with persistently or intermittent elevation of alanine aminotransferase (ALT) and/or HBV DNA >105 copies/mL. Mean stiffness was 4.83 ± 1.2 kPa in group 1 vs 8.53 ± …

AdultMalemedicine.medical_specialtyPathologyHepatitis B virusBiopsymedicine.disease_causeGastroenterologyDiagnosis DifferentialYoung Adultfibroscan hepatitis B hepatitis B virus transient elastography type B hepatitis HBeAgFibrosisVirologyInternal medicineBiopsymedicineHumansHepatitis B e AntigensHepatitis B AntibodiesAgedHepatitis B virusHepatitis B Surface AntigensHepatologymedicine.diagnostic_testbusiness.industryvirus diseasesAlanine TransaminaseHepatitis BMiddle Agedmedicine.diseaseHepatitis Bdigestive system diseasesInfectious DiseasesCross-Sectional StudiesFibroscan; hepatitis B virus; transient elastography; type B hepatitis HBeAgHBeAgLiverLiver biopsyCarrier StateElasticity Imaging TechniquesFemalebusinessTransient elastographyViral hepatitis
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Type-D personality and depersonalization are associated with suicidal ideation in the German general population aged 35–74: Results from the Gutenber…

2009

Suicidal ideation (SID) is a major risk factor for suicide attempts. Mental disorders are among the strongest correlates of suicide, with depression and anxiety disorders playing a major role. The present study aims to investigate the contribution of under researched factors contributing to SID such as depersonalization, Type-D personality and cardiovascular risk factors.Factors associated with SID were investigated in a sample of N=5000 participants (aged 35-74 years) of the community-based survey "Gutenberg Heart Study". The factors were assessed by self-report instruments, computer-assisted interviews and medical examination.7.5% of the sample reported SID over the last 2 weeks. In the u…

AdultMalemedicine.medical_specialtyPersonality InventoryPsychometricsmedia_common.quotation_subjectPopulationMyocardial InfarctionPoison controlCoronary DiseaseSuicidal IdeationMental distressGermanyDepersonalizationmedicineHumansPersonalityPsychiatryeducationSuicidal ideationAgedmedia_commonDepressive Disorder Majoreducation.field_of_studyType D personalityType A PersonalityType A and Type B personality theoryMiddle AgedPrognosisAnxiety DisordersHealth SurveysPsychiatry and Mental healthClinical PsychologyCross-Sectional StudiesPersonality DevelopmentSocioeconomic FactorsDepersonalizationFemalemedicine.symptomPsychologyClinical psychologyJournal of Affective Disorders
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YAP/TAZ activity in stromal cells prevents ageing by controlling cGAS-STING

2022

Ageing is intimately connected to the induction of cell senescence(1,2), but why this is so remains poorly understood. A key challenge isthe identification of pathways that normally suppress senescence, are lost during ageing and are functionally relevant to oppose ageing(3). Here we connected the structural and functional decline of ageing tissues to attenuated function of the master effectors of cellular mechanosignalling YAP and TAZ. YAP/TAZ activity declines during physiological ageing in stromal cells, and mimicking such decline through genetic inactivation of YAP/TAZ in these cells leads to accelerated ageing. Conversely, sustaining YAP function rejuvenates old cells and opposes the e…

AgingMechanotransductionActin-Related Protein 2; Cellular Senescence; Extracellular Matrix; Healthy Aging; Immunity Innate; Lamin Type B; Mechanotransduction Cellular; Nuclear Envelope; Signal Transduction; Aging; Membrane Proteins; Nucleotidyltransferases; Stromal Cells; Transcriptional Coactivator with PDZ-Binding Motif Proteins; YAP-Signaling ProteinsNuclear EnvelopeSettore MED/08 - Anatomia PatologicaYAP TAZ ageing C-GAS STINGMechanotransduction CellularArticleHealthy AgingInnateCellular SenescenceAdaptor Proteins Signal TransducingMultidisciplinaryLamin Type BImmunityMembrane ProteinsYAP-Signaling ProteinsPhosphoproteinsNucleotidyltransferasesImmunity InnateExtracellular MatrixTranscriptional Coactivator with PDZ-Binding Motif ProteinsActin-Related Protein 2CellularStromal CellsSignal Transduction
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The Jyväskylä Longitudinal Study of Personality and Social Development (JYLS)

2006

The Jyvaskyla Longitudinal Study of Personality and Social Development is an ongoing long-term study that began in 1968. From the very beginning, data have been collected within a framework of emotional and behavioral regulation. This chapter presents the framework model and its theoretical rationales. Data collection waves are described, first, from childhood to adolescence, and second, in adulthood. Results on continuity in socioemotional behavior and its developmental background, problem behavior and health, and positive development are presented so as not to overlap with results in the other chapters of this book. INTRODUCTION The title of the Jyvaskyla Longitudinal Study of Personality…

AgreeablenessExtraversion and introversionProsocial behaviorAdult developmentPersonality developmentmedia_common.quotation_subjectSocial changePersonalityType A and Type B personality theoryPsychologySocial psychologymedia_commonDevelopmental psychology
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On Hurwitz spaces of coverings with one special fiber

2009

Let X X' Y be a covering of smooth, projective complex curves such that p is a degree 2 etale covering and f is a degree d covering, with monodromy group Sd, branched in n + 1 points one of which is a special point whose local monodromy has cycle type given by the partition e = (e1,...,er) of d. We study such coverings whose monodromy group is either W(Bd) or wN(W(Bd))(G1)w-1 for some w in W(Bd), where W(Bd) is the Weyl group of type Bd, G1 is the subgroup of W(Bd) generated by reflections with respect to the long roots ei - ej and N(W(Bd))(G1) is the normalizer of G1. We prove that in both cases the corresponding Hurwitz spaces are not connected and hence are not irreducible. In fact, we s…

AlgebraCombinatoricsWeyl groupsymbols.namesakeMonodromyGeneral MathematicssymbolsPartition (number theory)Settore MAT/03 - GeometriaCentralizer and normalizerMathematicsHurwitz spaces connected components special fiber Weyl groups of type B_d
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